ABSTRACT
To determine the frequency of raised serum ferritin level in patients with metabolic syndrome. Case series study. Liaquat University Hospital Hyderabad. All the patients with metabolic syndrome for >/= 01 year duration, >/=20 years of age and of either sex were recruited and entered in the study. The metabolic syndrome was detected according to the NCEP-ATP III protocol. After confirmation of metabolic syndrome, the 2cc venous blood sample was taken in a sterilize 5cc disposable syringe, labeled it and sent to laboratory for evaluation of serum ferritin levels. The data was analyzed in SPSS 16 and the frequency and percentage was calculated. Total one hundred patients with metabolic syndrome were evaluated for serum ferritin level during the study period. The mean +/- SD for age of patients with metabolic syndrome was 52.73 +/- 7.83 while the mean age +/- SD of patient with raised ferritin level was 50.23 +/- 8.21. The majority patients were 30-49 age group with female predominance [p<0.01] and exist four component of metabolic syndrome. The ferritin was raised in 60 patients with female predominance [p<0.04]. The mean +/- SD of raised ferritin level in male and female population was 350.10 +/- 19.38 and 270.34 +/- 34.39 [p<0.01]. The raised serum ferritin level was identified [60%] with female predominance in patients of metabolic syndrome
Subject(s)
Humans , Female , Male , Middle Aged , Adult , Ferritins/blood , IronABSTRACT
To evaluate the frequency of hyponatremia and its prognostic importance in ST elevation myocardial infarction. Six months. Case series. Tertiary care hospital Hyderabad. All the cases with ST elevation myocardial infarction admitted in the CCU were recruited and evaluate for serum sodium level at admission and then at 24, 48 and 72 hours. The data was analyzed in SPSS 16 and the frequency and percentage was calculated. One hundred patients with acute myocardial infarction were recruited and assessed for sodium level. The mean age +/- SD of whole population was 57.52 +/- 9.51 whereas in male and female population it was 58.72 +/- 7.53 and 53.84 +/- 7.93 respectively. The sodium level was 130.21 +/- 3.42 and 127.41 +/- 4.21 in male and female population. The p-value was statistically significant [<0.01] in context to age and sex whereas the age in context to hyponatremia is non significant [p=0.77]. The hyponatremia and its severity was statistically significant in context to sex [p=0.04] and duration of the myocardial infarction [p=0.03]. The serum sodium level in context to duration of MI was also significant [p=0.03] whereas the mortality at the end of 30 days was 11% of which 02 patients had normal sodium level while the 09 had low sodium level [hyponatremia]. Hyponatremia in patients with acute STEMI is a important predictor of thirty days mortality
ABSTRACT
To determine the cardiac manifestations in patients with pulmonary tuberculosis. Case series study. Jan 2014 to June 2014. Liaquat University Hospital Hyderabad. All the patients presented with shortness of breath, cough with sputum, fever, haemoptysis, anorexia and weight loss were recruited and then the subjects with early morning sputum positive for acid fast bacilli and radiological lesions suggestive of pulmonary tuberculosis, of ?20 years of age and either gender were enrolled and entered in the study. The data was analyzed in SPSS 16 and the frequency and percentage was calculated. Total one hundred patients with pulmonary tuberculosis were evaluated for cardiac manifestation during six months study period. The mean +/- SD for age of patients with pulmonary tuberculosis was 45.21 +/- 8.95. The mean age +/- SD of patient with cardiac manifestations was 48.95 +/- 5.53. The majority of the subjects were in 30-49 years age group with male predominance [p<0.01]. The electrocardiographic findings were observed in 72/100 [72%] patients whereas echocardiographic changes were observed in 50/72 [69.4%] patients with pulmonary tuberculosis. The common ECG findings identified were tachycardia 30.5%, P-pulmonale 12.5% and PR prolonged in 9.7% patients with tuberculosis whereas the common echocardiographic findings noticed were pericardial effusion 42% and multiple abnormalities in 24% subjects with tuberculosis. The sinus tachycardia, cor-pulmonale and low voltage QRS complexes were predominant abnormalities on electrocardiograph whereas pericardial effusion was the common abnormality on echocardiography in patients with pulmonary tuberculosis
ABSTRACT
Objectives: to determine the frequency of hyperuricemia in patients with essential hypertension
Study Design: cross sectional descriptive
Period: six months study
Setting: liaquat University Hospital Hyderabad
Patients and Methods: all the patients with essential hypertension visited at cardiac OPD / admitted in the ward were further evaluated for serum uric acid level. The data was analyzed in SPSS 16 and the frequency and percentage was calculated
Results: during six months study period, total one hundred and eighty [180] patients with essential hypertension were recruited and study for uric acid level. The mean age +/- SD for overall population was 52.84 +/- 8.72 whereas it was 55.83 +/- 7.93 and 50.75 +/- 8.95 in male and female population respectively. The mean +/- SD of systolic and diastolic blood pressure [mmHg] in overall population was 160.50 +/- 12.74 and 100.70 +/- 5.95 respectively. The mean +/- SD serum uric acid level in overall population was 13.74 +/- 4.83 while it was 11.74 +/- 6.44 and 14.43 +/- 4.31 in male and female population respectively]. The male population was predominant in relation to age [p=0.02], the hyperuricemia was identified in 117/180 [65%] patients and it is statistically significant in context to age [p<0.01] and gender [p<0.05] whereas mean +/- SD of systolic and diastolic blood pressure was also significant in relation to hyperuricemia
Conclusion: there is a relationship between hyperuricemia and hypertension and shown that the serum uric acid level was significantly increased in patients with essential hypertension
ABSTRACT
To evaluate the serum homocysteine level in patients with hypertension at Liaquat University Hospital Hyderabad. This six months study was conducted at Liaquat University Hospital Hyderabad. All the hypertensive patients for >/= 01 years duration, of >/= 35 years of age and either gender visited at the cardiac logy OPD or admitted in cardiac ward were registered and evaluated for their homocysteine level. The normal plasma homocysteine level is between 5 to <15 micro mol/L. The results of plasma homocysteine level were interpreted as normal, moderate, intermediate and severe according to the reference range [moderate = 15 to 30 micro mol/L; intermediate = 30 to 100 micro mol/L; severe = >100 micro mol/L]. The frequency and percentage was calculated for hyperhomocysteinemia in hypertensive patients. The chi-square and independent t-test was applied between categorical variables at 95% confidence interval and the p-value
Subject(s)
Humans , Female , Male , Homocysteine/bloodABSTRACT
To determine the serum zinc level in patients with acute myocardial infarction at Liaquat University Hospital Hyderabad. This six months study was conducted on the patients with acute myocardial infarction presented at coronary care unit [CCU] of Liaquat University Hospital Hyderabad. All the patients with myocardial infarction, of >/= 30 years of age and either gender diagnosed as acute myocardial infarction were admitted and evaluate for their serum zinc level by taking 2cc fasting venous blood sample on admission and at one or two day interval thereafter. The data entered, saved and analyze in SPSS version 11.00. Total 142 patients with acute MI were registered for study. Of these 92[64.8%] were males and 50 [35.2%] were females. The mean age +/- SD for male and female was 54.98 +/- 11.88 and 50.52 +/- 9.85 respectively. Regarding plasma zinc level, hypozincemia [low zinc level] was observed in 90[63%] patients, of which 53[58.9%] were males and 37[41.1%] were females while the 52[37%] subjects had normozincemia [normal zinc level]. In 33 [36.7%] patients the serum zinc was low at admission, 38[42.4%] patients had hypozincemia on 3rd day of admission while 19[21.1%] had low serum zinc level on 5th day of admission. The mean +/- SD for serum zinc level in overall population was 9.78 +/- 2.31 and the mean +/- SD of patients with hypozincemia was 7.85 +/- 3.42, whereas the mean +/- SD of patients with normozincemia was 16.85 +/- 2.53. During hospitalization the complications of acute MI identified in hypozincemic population were cardiac arrhythmias, cardiac failure, pericarditis, recurrent infarction, thromboembolism and mitral regurgitation. It is observed that serum zinc level appears to be low in patients with acute myocardial infarction